S.I.M.S. s.r.l., Italy
S.I.M.S. – a product/project-related co-operation partner for Active Pharmaceutical Ingredients and Intermediates.
The Company:
S.I.M.S. was founded in Florence in 1937 and it now has a strong presence through a wide distribution network in the main pharmaceutical markets all over the world. Since the 80s, S.I.M.S. has gained increasing recognition in the custom manufacture of APIs and Intermediates with major pharmaceutical companies. Advanced technologies, a total reactor volume of 280 m³ and highly qualified personnel are at the customer’s disposal to fulfill all the individual and exclusive requirements from laboratory to industrial scale.
Specific Strengths:
- Acylation (Friedel-Crafts, Houben-Hoesch, Schotten-Baumann, Fries)
- Halogenations
- C-/N-/O-Alkylations
- Grignard Reactions
- Vilsmeier Reactions
- Catalytic Hydrogenations
- Reactions with Alkaline Cyanides
- Oxidations with Hydrogen Peroxide and Chromic Anhydride
- Reductions (Bechamp, Birch)
- Reactions in liquid Ammonium
Since 1972 S.I.M.S. has been regularly inspected by the FDA and has more than 20 DMFs registered with the Agency. S.I.M.S. is conscious of the extreme importance of complying with the increasingly strict rules of cGMP and it is operating in this direction to be ahead of competition.
 |
 |
