Simafex, France
Simafex – an exclusive partner for Active Pharmaceutical Ingredients and Intermediates.
The Company:
As a subsidiary of the Guerbet pharmaceutical laboratories, Simafex is a fine chemical manufacturer focused on custom synthesis and contract manufacture of APIs and advanced intermediates for the pharmaceutical industry. Today, Simafex employs more than 90 people. The total reactor capacity amounts to 72 m³.
Specific Strengths:
- Iodine Chemistry
- Oxidations (DDQ, Diacetoxyiodobenzene, TMSOI, Dess-Martin with stabilized reagent / SIBX)
- Cyanations (Hydrogencyanide in situ)
- Cyclopropanation
- Organometallic
- Macrocyclisation
- Chiral synthesis
- Palladium Coupling
- Dehydrogenation
- Epoxidation
In the respect of the environment, Simafex has demonstrated its long-term ability to supply the world's leading pharmaceutical companies at best quality standards. The necessity to conform to cGMP guidelines is self-evident. Certification according to ISO 9000/9002 was accomplished in 1997. Further Simafex has been inspected successfully twice by the French health authorities.
About 60 % of the total business is generated with custom synthesis projects whereas 40 % are realised with line products.
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