Overview

Bosentan

CAS

147536-97-8, 157212-55-0, 1196074-08-4

Status

Development

Bosentan is an endothelin receptor antagonist, displacing endothelin-1. This removes the effect of endothelin-1. As a result, blood vessels dilate and (pulmonary) blood pressure decreases. Bosentan is an orphan drug used to treat rare pulmonary arterial hypertension (pulmonary blood pressure), it has recently been used quite successfully for scleroderma (autoimmune connective tissue disease).

Description

Formula

C27H29N5O6S

Molecular weight

551.61 g/mol

Molecular size

small

Controlled Substance

no

Precursor

no

Indications

Antihypertensives

Your Contact

Marius Hang

Marius Hang

International Division
Director API Export

Midas Pharma GmbH
Rheinstr. 49
55218 Ingelheim
Germany
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