Cladribine is a chlorinated analogue of the DNA building block Deoxyadenosin, which only becomes an active metabolite in the body. By using DNA nucleotide analogues, the immune system and cell growth are weakened. Cladribine also leads to apoptosis (programmed cell death) in tumor cells due to its cytostatic effect. This is used to treat hair cell leukemia and multiple sclerosis.
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