Raloxifene hydrochloride is a synthetic, nonsteroidal, selective estrogen receptor modulator. It is used to treat and prevent osteoporosis in postmenopausal women. There is evidence that Raloxifene additionally reduces the risk of breast cancer and has a positive effect on the cardiovascular risk of postmenopausal women. In 2018, a meta-analysis showed that it can also noticeably reduce the symptoms of schizophrenia. Dose adjustment is not necessary in the elderly, which is why it is suitable for long-term treatment.